Research - Paediatric Nephrology

Key areas of Research

The department of Pediatric Nephrology is at the forefront of basic, translational and clinical research in the country. Even in research “it’s all about patients” with the overarching focus towards better understanding of renal diseases relevant to our population as well as improving our clinical management of children with kidney diseases. One of the unique features of our research program is to conduct “bench to bedside” studies. The department in collaboration with Division of Molecular Medicine, St. John’s Research Institute provides a robust research environment as we attempt to combine the two world of molecular and cellular science with the clinical science to improve care for children with kidney diseases. We use cell biology, genetics and developmental aspects of kidney disease to understand the diseases.

Our department has received funding from various international and national funding agencies for our research. These include Canadian Institute of Health and Research, International Society of Nephrology, Medical Research Council of United Kingdom, Department of Biotechnology, Indian Council of Medical Research and Council for Scientific and Industrial Research.

Key Achievements

Establish “first of its kind” basic science laboratory dedicated to nephrology in a medical college and teaching hospital campus in India with active involvement of clinicians
Establishment of technology platforms for Molecular and Cellular Research
First to report of genetic mutations in steroid resistant nephrotic syndrome in Indian population.
Launched the Next Generation Sequencing (NGS) service for genetic diagnosis of Nephrotic Syndome
Cohort building with associated human clinical specimen Bio-Repository in Nephrotic Syndrome, Chronic Kidney Disease and Acute Kidney Injury

Focus Areas of Research
Vitamin D dosing in chronic kidney disease
Malnutrition- inflammation complex in chronic kidney disease
Cardiovascular disease in chronic kidney disease
Quality of life in end –stage renal disease

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