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Overview
Department of Clinical Haematology & Bone Marrow Transplant St. John’s Medical College Hospital, Bengaluru
Introduction
The Department of Clinical Haematology and Bone Marrow Transplant began at St. John’s in March 1990. It became a separate department in May 2022. Today, it stands as a center of excellence in patient care, research, and academic leadership, offering advanced treatments for complex blood disorders and training the next generation of haematologists.
Highlights at a Glance
- Faculty: 5 core faculty + adjunct professors
- All types of Stem Cell Transplants: : Both Autologous and Allogenic, Haploidentical and MUD, CAR-T Cell therapy
- Hemophilia Patients Supported: 715+ through WFH Humanitarian Aid Program
- Funds Raised (2022–23): ₹800 Lakhs for patient care and research.
- Publications: 100+ peer‑reviewed papers in leading journals
Vision & Future
The department is committed to:
- Expanding bone marrow transplantation services.
- Advancing precision medicine in Hematology through genomics and translational research.
- Strengthening patient outreach and humanitarian programs.
- Training the next generation of haematologists to lead nationally and globally.
- Innovations in Gene therapy and other low-cost cutting-edge therapeutics.
Summary: The Department of Clinical Hematology and Bone Marrow Transplant at St. John’s stands as a beacon of patient care, research, and academic excellence. Guided by the leadership of Dr. Cecil Ross and Dr Alok Srivastava along with Dr Chaitanya HB and a dedicated faculty team, the department continues to make a profound impact on Hematology in India and beyond.
2. Highlights at a Glance
A visually engaging stats panel with icons:
- Faculty: 5 (including adjunct professors)
- Postgraduates: 6 DrNB students
- Stem Cell Transplants: both Autologous and Allogenic, Haploidentical and MUD, CAR-T Cell therapy
- Patients Supported: 715 Hemophilia patients (WFH Program)
- Funds Raised (2022–23): ₹800 Lakhs
- Publications: 100+ peer‑reviewed papers
Our Team
Unit Head
Professor & HOD
Dr. Cecil Reuben RossProfessor & Head, Department of Clinical Hematology and Bone Marrow TransplantSt. John’s Medical...
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Professor
Dr. Alok SrivastavaSenior Consultant, Department of Clinical HaematologyHead, Haematology Research Unit, St. John’s ...
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Associate Professor
Dr. Seetharam AnandramAssociate Professor, Department of Clinical HaematologySt. John’s Medical College Hospital, Ben...
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Assistant Professor
Dr. Sanjukta Rao, Assistant Professor, Department of Clinical Haematology and Bone Marrow TransplantSt. John’s Medica...
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Assistant Professor
Dr. Chaitanya H. BalakrishnanAssistant Professor, Department of Clinical Haematology and Bone Marrow TransplantSt. J...
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Assistant Professor
Clinical Haematology DepartmentST. JOHN'S MEDICAL COLLEGE HOSPITALKoramangala, Bengaluru, Karnataka560-034
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Services
Out- Patient Services
MORNING OUT-PATIENT SERVICESDr. Cecil R Ross- Monday and Friday 9 AM to 1-00 PM Dr. Alok Srivastava MD, FRACP, FRCPA, FRCP- Wednesday( fast-track OPD)10:30 AM to 1-00 PM - Wednesday( Fast-track OPD: Appointments through hematology.secretary@stjohns.in)Dr. Seetharam Anandram- Tuesday, Thursday 9 AM to 1-00 PMDr. Chaitanya H Balakrishnan- Monday, Friday and Saturday 9 AM to 1-00 PMEVENING OUT-PATIENT SERVICESDr. Se...
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Publications
An ASTCT, CIBMTR, EBMT, and APBMT Consensus Statement Defining Response Criteria for Hematopoietic Cell Transplantation Associated Thrombotic Microangiopathy (TA-TMA) Directed Therapy
Michelle L Schoettler 1, Eleni Gavriilaki 2, Enric Carreras 3, Cho Bo-Kyoung 4, Christopher E Dandoy 5, Vincent T Ho 6, Sonata Jodele 5, Ivan Moiseev 7, Isabella Sánchez-Ortega 8, Alok Srivastava 9, Yoshiko Atsuta 10, Paul A Carpenter 11, John Koreth 6, Nicolaus Kröger 12, Per Ljungman 13, Kristen Page 14, Uday Popat 15, Bronwen E Shaw 16, Ana Maria Sureda 17, Robert Soiffer 6, Sumithira Vasu 18 Activated prothrombin complex concentrate in patients receiving emicizumab prophylaxis: from evidence to clinical practice
Robert F Sidonio Jr 1, Guy Young 2, Carmen Escuriola Ettingshausen 3, Johnny Mahlangu 4, Margareth C Ozelo 5, Alok Srivastava 6, Jerzy Windyga 7, Hye-Youn Lee 8, Aurelia Lelli 8, Steven W Pipe 9 Cross-Sectional Survey of Haemophilia Treatment Centres (HTCs) in India: Towards a Context‑Sensitive Stratification Model
M Joseph John 1, Chandrakala Shanmukhaiah 2, Toshirenla Aier 3, Neeraj Sidharthan 4, Renu Saxena 5, Shashikant Apte 6, Aby Abraham 7, Naresh Gupta 8, Soniya Nityanand 9, Cecil Ross 10, Tulika Seth 11, Alok Srivastava 10 Total and Neutralizing Antibody Seroprevalence of Hepatotropic Adeno-Associated Virus Among Healthy and Hemophilia A or B Population from India
Hubert Darius J Daniel 1 2, Jaffar Farzana 1, Rajesh Kannangai 2, Sanjay Kumar 1, Kavitha M Lakshmi 3, Charnitkaur B Jashal 4, Hemant Dhamne 4, Varun Lahoti 4, Deepak Kanjwani 4, Aby Abraham 3, Kirsten Coleman 5, Arun Srivastava 6, Alok Srivastava 1 3, Asha Mary Abraham Corticosteroid use to mitigate transaminitis-associated decline in FVIII levels following valoctocogene roxaparvovec gene therapy: clinical practice guidance
Barbara A Konkle 1, Flora Peyvandi 2, Graham R Foster 3, Cedric Hermans 4, Vincenzo La Mura 2, Andrew D Leavitt 5, David Lillicrap 6, Johnny Mahlangu 7, Margareth C Ozelo 8, Steven Pipe 9, Michael Recht 10, Alok Srivastava 11, Guy Young 12, Wolfgang Miesbach Safety and efficacy of a fitusiran antithrombin-based dose regimen in people with hemophilia A or B: the ATLAS-OLE study.
Young G 1 , Kavakli K 2 , Klamroth R 3 , Matsushita T 4 , Peyvandi F 5 , Pipe SW 6 , Rangarajan S 7 , Shen MC 8 , Srivastava A 9 , Sun J 10 , Tran H 11 , You CW 12 , Zülfikar B 13 , Menapace LA 14 , Zhang C 15 , Shen Y 16 , Puurunen M 14 , Demissie M 14 , Kenet G Activated prothrombin complex concentrate in patients receiving emicizumab prophylaxis: from evidence to clinical practice
Robert F Sidonio Jr 1, Guy Young 2, Carmen Escuriola Ettingshausen 3, Johnny Mahlangu 4, Margareth C Ozelo 5, Alok Srivastava 6, Jerzy Windyga 7, Hye-Youn Lee 8, Aurelia Lelli 8, Steven W Pipe 9 Guidelines for management of hemophilia-why, what, and how?
Alok Srivastava 1, Johnny Mahlangu 2, Steven W Pipe 3 Cross-Sectional Survey of Haemophilia Treatment Centres (HTCs) in India: Towards a Context‑Sensitive Stratification Model
M Joseph John 1, Chandrakala Shanmukhaiah 2, Toshirenla Aier 3, Neeraj Sidharthan 4, Renu Saxena 5, Shashikant Apte 6, Aby Abraham 7, Naresh Gupta 8, Soniya Nityanand 9, Cecil Ross 10, Tulika Seth 11, Alok Srivastava 10 Quality of Life and Treatment Satisfaction in People With Haemophilia on Fitusiran Prophylaxis: Evidence From a Subset of ATLAS-OLE Trial Participants Mainly From India
Alok Srivastava 1, Savita Rangarajan 2 3, Cecil Ross 4, Shariq Ali 5, Shauna Andersson 6, Laurel A Menapace 6, Marja Puurunen 6, Marion Afonso 7 Engineering safe anti-CD19-CD28ζ CAR T cells with CD8a hinge domain in serum-free media for adoptive immunotherapy
Muthuganesh Muthuvel 1 2, Thamizhselvi Ganapathy 3, Trent Spencer 4, Sunil S Raikar 4, Saravanabhavan Thangavel 3, Alok Srivastava 3 5 6, Sunil Martin 1 Mild or moderate hemophilia is not always a mild or moderate bleeding disorder: Back to the clinical phenotype
Francesco Rodeghiero 1,✉, Lisanna Ghiotto 1, Luca Pontalto 1, Alessandro Casini 2, Giancarlo Castaman 3, Rezan Abdul‐Kadir 4, Erik Berntorp 5, Imre Bodó 6, Manon Degenaar‐Dujardin 7, Karin Fijnvandraat 8,9, Paolo Gresele 10, Nigel S Key 11, Riitta Lassila 12, Frank W G Leebeek 13, David Lillicrap 14, Mike Makris 15, Stephan Meijer 16, Diego Mezzano 17, Patrizia Noris 18, Ingrid Pabinger 19, Margaret V Ragni 20, David Silva 21, Alok Srivastava 22, Alberto Tosetto 23, Jerzy Windyga 24, Barbara Zieger 25 Evaluation of safety and efficacy of multiple intravenous and intraosseous doses of foetal liver-derived mesenchymal stem cells in children with severe osteogenesis imperfecta : the BOOST2B clinical trial protocol
Vrisha Madhuri 1 2 3, Sowmya Ramesh 1 2, Annika Goos 4, Thomas V Paul 5, Shyamkumar Nidugala Kesava 6, Vikram Mathews 7, Lilian Walther-Jallow 4, Cecilia Götherström 4; BOOST2B Study Group; Åsa Ekblad 8, Vignesh Kumar 1 9, Suhasini Ganesh 1 9, Lakshmi Loganathan 1 9, Renita Raymond 1 9, Ashis Kumar 1 9, Dolly Daniel 10, Nihal Thomas 5, Deeptiman James 1, Madhavi Kandagaddala 6, Priya Mammen 11, Antonisamy B 12, Alok Srivastava 9 7 Outcomes in patients undergoing hematopoietic stem cell transplantation for myelodysplastic syndromes
Sujith Karumathil 1, Uday Kulkarni 1, Sushil Selvarajan 1, Sharon Lionel 1, Anup J Devasia 1, Fouzia N Aboobacker 1, Kavitha M Lakshmi 1, Anu Korula 1, Alok Srivastava 1, Aby Abraham 1, Vikram Mathews 1, Biju George 1 Adeno-associated virus-based gene therapy for hemophilia-addressing the gaps
Wolfgang Miesbach 1, Paul Batty 2 3, Pratima Chowdary 3, Sylvia Fong 4, Radoslaw Kaczmarek 5 6, Frank W G Leebeek 7, Brian Long 8, Johnny Mahlangu 9, Mike Makris 10, Glenn F Pierce 11, Steven W Pipe 12, Alok Srivastava 13, Jan Voorberg 14, Flora Peyvandi 15 16 Lentiviral Gene Therapy with CD34+ Hematopoietic Cells for Hemophilia A
Srivastava A, Abraham A, Aboobacker F, Singh G, Geevar T, Kulkarni U, Selvarajan S, Korula A, Dave RG, Shankar M, Singh AS, Jeba A, Kumaar N, Benjamin C, Lakshmi KM, Srivastava VM, Shaji RV, Nair SC, Brown HC, Denning G, Lollar P, Doering CB, Spencer T. Enhanced fetal hemoglobin production via dual-beneficial mutation editing of the HBG promoter in hematopoietic stem and progenitor cells for β-hemoglobinopathies
Prathibha Babu Chandraprabha # 1 2, Manoj Kumar K Azhagiri # 1 2, Vigneshwaran Venkatesan 1 2, Wendy Magis 3, Kirti Prasad 1 2, Sevanthy Suresh 1 2, Aswin Anand Pai 4, Srujan Marepally 1, Alok Srivastava 1 4, Kumarasamypet Murugesan Mohankumar 1, David I K Martin 3, Saravanabhavan Thangavel 5 Impact of the COVID-19 outbreak on the field of hematopoietic cell transplantation in the Asia-Pacific region: APBMT Activity Survey 2020/2021
Iida M, Ho A, Huang XJ, Liu K, Lv M, Huang H, Kuwatsuka Y, Moon JH, Choi YS, Lee JW, Khattry N, M Lakshmi K, Wilcox L, Hamidieh AA, Behfar M, Ko BS, Ho KW, Gan GG, Bunworasate U, Hongeng S, Anurathapan U, Farzana T, Sim J, Lee V, Leung MKG, Dung PC, Huynh VM, Rathnayake W, Abeysinghe P, Bravo MR, Dumagay T, Gyi AA, Santosa D, Ardini D, Poudyal BS, Akter M, Batshkh K, Drokov M, Li CC, Okamoto S, Srivastava A, Dodds A, Atsuta Y; Registry Committee of the Asia‑Pacific Blood and Marrow Transplantation Group (APBMT) Microarray analysis reveals distinct immune signatures in BCR-ABL positive and negative myeloproliferative neoplasms
Cecil Ross 1, Mugdha Sharma 1, John Paul 1, Sweta Srivastava 2 "Effect of Point Mutation on Structure-Function Correlation of Hemoglobin Variants, HbE and HbD Punjab Amino Acids"
Sreekala Narayanan, Boby Mathew, Bindu Y. Srinivasu, Vijay Bhat, Cecil Ross & Amit Kumar Mandal Congenital hemolytic anemia in pregnancy – experience in a tertiary care hospital in South India
Rao Preethi Venkatachala 1, C N Sheela 1, Seetharam Anandram 2, Cecil R Ross 2 Clinical phenotype, fibrinogen supplementation, and health-related quality of life in patients with afibrinogenemia
Alessandro Casini 1 2, Sylvia von Mackensen 3, Cristina Santoro 4, Claudia Djambas Khayat 5, Meriem Belhani 6, Cecil Ross 7, Akbar Dorgalaleh 8, Arshi Naz 9, Ekrem Ünal 10 11, Magy Abdelwahab 12, Elise Dupuis Lozeron 13, Nathalie Trillot 14, Sophie Susen 15, Flora Peyvandi 16, Philippe de Moerloose 2; QualyAfib Study Group Pharmacokinetics, efficacy and safety evaluations of a new human plasma derived fibrinogen concentrate (FIB Grifols) in adult patients with congenital afibrinogenemia
Ross CR, Subramanian S, Navarro-Puerto J, Subramanian K, Kalappanavar NK, Khayat CD, Acharya SS, Peyvandi F, Rucker K, Liang W, Vilardell D, Trimm S, Ayguasanosa J. Efficacy and Safety of Fitusiran Prophylaxis, an siRNA Therapeutic, in a Multicenter Phase 3 Study (ATLAS-INH) in People with Hemophilia A or B, with Inhibitors (PwHI)
Guy Young, Alok Srivastava, Kaan Kavakli, Cecil Ross, Jameela Sathar, Huyen Tran, Runhui Wu, Jing Sun, Stacey Poloskey, Zhiying Qui, Salim Kichou, Shauna R. Andersson, Baisong Mei, Savita Rangarajan Gene expression profiling of CD34+ cells from Myeloproliferative Neoplasm patients
Mugdha Sharma 1, Chandra Bhavani 2, Srinag Bangalore Suresh 1, John Paul 1, Lokendra Yadav 3, Cecil Ross 1, Sweta Srivastava 3 Gene expression profiling of CD34+ cells from Myeloproliferative Neoplasm patients
Mugdha Sharma 1, Chandra Bhavani 2, Srinag Bangalore Suresh 1, John Paul 1, Lokendra Yadav 3, Cecil Ross 1, Sweta Srivastava 3 Autoimmune hemolytic anaemias in pregnancy – experience in a tertiary care hospital in South India
Rao Preethi Venkatachala, C. N. Sheela, Seetharam Anandram & Cecil R. Ross Turoctocog alfa is safe for the treatment of Indian patients with hemophilia A : Guardian 10 trial results
M Joseph John 1, Prantar Chakrabarti 2, Shashikant Apte 3, Maitreyee Bhattacharyya 4, Chandrakala S 5, Trine Hansen 6, Rohan Kolla 7, Cecil Ross 8, Tulika Seth 9, Neeraj Siddharthan 10, Aby Abraham 11 "Efficacy and safety of fitusiran prophylaxis in people with haemophilia A or haemophilia B with inhibitors (ATLAS-INH): a multicentre, open-label, randomised phase 3 trial"
Guy Young 1, Alok Srivastava 2, Kaan Kavakli 3, Cecil Ross 4, Jameela Sathar 5, Chur-Woo You 6, Huyen Tran 7, Jing Sun 8, Runhui Wu 9, Stacey Poloskey 10, Zhiying Qiu 11, Salim Kichou 12, Shauna Andersson 13, Baisong Mei 13, Savita Rangarajan 14 Association of exosomal miR-96-5p and miR-146a-5p with the disease severity in dengue virus
Aunji Pradhan 1, Ashish Aneja 1, Sahana Ghosh 2, Himadri Devvanshi 3, Deepika C 1, Risabh Sahu 1, Celil Ross 4, Pallavi Kshetrapal 3, Arindam Maitra 2, Saumitra Das 1 2 Reduced Volume and Faster Infusion Rate of Activated Prothrombin Complex Concentrate: A Phase 3b/4 Trial in Adults with Hemophilia A with Inhibitors.
Bülent Zülfikar 1, Johnny Mahlangu 2, Salim Mohamed Nekkal 3, Cecil Ross 4, Noppacharn Uaprasert 5,6, Jerzy Windyga 7, Carmen Escuriola Ettingshausen 8, Bettina Ploder 9, Aurelia Lelli 10, Hanna T Gazda 11,✉ Pregnancy outcomes of mothers with immune thrombocytopenia
Shashikala Karanth Department of Obstetrics and Gynecology, St. John’s Medical College and Hospital, Bangalore, Karnataka, India Christy Vijay Department of Obstetrics and Gynecology, St. John’s Medical College and Hospital, Bangalore, Karnataka, India Chaitanya Harita Department of Medicine, St. John’s Medical College and Hospital, Bangalore, Karnataka, India Jaya S. Mol Department of Obstetrics and Gynecology, St. John’s Medical College and Hospital, Bangalore, Karnataka, India A comprehensive care pathway of gene therapy for hemophilia based on current guideline documents and summary of product characteristics: communication from the ISTH SSC working group on gene therapy.
Caroline M.A. Mussert 1 , Wolfgang Miesbach 2 , Pratima Chowdary 3 4 , David Lillicrap 5 , Johnny Mahlangu 6, Flora Peyvandi 7 8 , Steven W. Pipe 9, Alok Srivastava 10, Jan Voorberg 11, Glenn F. Pierce 12 , Radoslaw Kaczmarek 13 14 , Paul Batty 3 4 , Ilaria Cutica 15 , Amit Nathwani 3 4, Frank W.G. Leebeek 16 A comprehensive care pathway of gene therapy for hemophilia based on current guideline documents and summary of product characteristics: communication from the ISTH SSC working group on gene therapy.
Caroline M.A. Mussert 1 , Wolfgang Miesbach 2 , Pratima Chowdary 3 4 , David Lillicrap 5 , Johnny Mahlangu 6, Flora Peyvandi 7 8 , Steven W. Pipe 9, Alok Srivastava 10, Jan Voorberg 11, Glenn F. Pierce 12 , Radoslaw Kaczmarek 13 14 , Paul Batty 3 4 , Ilaria Cutica 15 , Amit Nathwani 3 4, Frank W.G. Leebeek 16 NuPOWER (Nuwiq for Perioperative management Of patients With haemophilia A on Emicizumab Regular prophylaxis): protocol for an open-label, single-arm, multicentre study
Alok Srivastava1,2, Angela Kanny3, Florian Langer4, Cornelia Kubicek-Hofmann5, María Teresa Álvarez Román6, Ramiro Núñez Vázquez7, Ana Boban8,9, Violeta Dejanova-Ilijevska10, Predrag Miljić11,12, Jessica Garcia13, Susan Halimeh14, Nicolas Drillaud15, Jean-Baptiste Valentin16, Maria Elisa Mancuso17,18, Giancarlo Castaman19, Rita Carlotta Santoro20, Anna-Elina Lehtinen21, Aby Abraham22, Mariko Hashimoto23, Sigurd Knaub24 No Data available for Book chapters.
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Speciality Clinics
Speciality Clinics
- Hemophilia Clinic
- Bone Marrow Transplant Clinic
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