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Outcomes of Biosynthetic and Synthetic Mesh in Ventral Hernia Repair
Dharshan Sivaraj, Katharina S Fischer, Trudy S Kim, Kellen Chen, Seth S Tigchelaar, Artem A Trotsyuk, Geoffrey C Gurtner, Gordon K Lee, Dominic Henn†, Rahim S Nazerali The introduction of mesh for reinforcement of ventral hernia repair (VHR) led to a significant reduction in hernia recurrence rates. However, it remains controversial whether synthetic or biologic mesh leads to superior outcomes. Recently, hybrid mesh consisting of reinforced biosynthetic ovine rumen (RBOR) has been developed and aims to combine the advantages of biologic and synthetic mesh; however, outcomes after VHR with RBOR have not yet been compared with the standard of care.
Methods:
We performed a retrospective analysis on 109 patients, who underwent VHR with RBOR (n = 50) or synthetic polypropylene mesh (n = 59). Demographic characteristics, comorbidities, postoperative complications, and recurrence rates were analyzed and compared between the groups. Multivariate logistic regression models were fit to assess associations of mesh type with overall complications and surgical site occurrence (SSO).
