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Estimation of protein requirements in Indian pregnant women using a whole-body potassium counter

Groups and Associations Kuriyan R, Naqvi S, Bhat KG, Thomas T, Thomas A, George S, Nagarajarao SC, Sachdev HS, Preston T, Kurpad AV
National Library of Medicine 2019

BACKGROUND:
The 2007 WHO/FAO/UNU recommendation for the Estimated Average Requirement (EAR) of additional protein during pregnancy for a gestational weight gain (GWG) of 12 kg (recalculated from a GWG of 13.8 kg) is 6.7 and 21.7 g.d-1 in the 2nd and 3rd trimesters respectively.  This EAR is based on measurements of potassium accretion in high-income country (HIC) pregnant women. It is not known if low to middle income country (LMIC), but well-nourished, pregnant women have comparable requirements.   

OBJECTIVE:
To estimate total body potassium (TBK) accretion during pregnancy in Indian pregnant women, using a whole-body potassium counter (WBKC), to measure their additional protein EAR.

DESIGN:
Well-nourished pregnant women (20-40 years, n = 38, middle socioeconomic stratum) were recruited in the first trimester of pregnancy. Anthropometric, dietary and physical activity measurements, and measurements of TBK using a WBKC, were performed at each trimester and at birth. 

RESULTS:
The mid-trimester weight gain was 2.7 kg and 8.0 kg in the 2nd and 3rd trimesters, for an average 37 week GWG of 10.7 kg and a mean birth weight of 3.0 kg.  Protein accretion was 2.7 and 5.7 g.d-1, for an EAR of 8.2 and 18.9 g.d-1 in the 2nd and 3rd trimesters, respectively. The additional protein EAR calculated for a GWG of 12 kg, was 9.1 and 21.2 g.d-1 in the 2nd and 3rd trimesters, respectively.

CONCLUSIONS:
The additional protein requirements of well-nourished Indian pregnant women for a GWG of 12 kg in the 2nd and 3rd trimesters were similar to the recalculated 2007 WHO/FAO/UNU requirements for 12 kg. 

https://www.ncbi.nlm.nih.gov/pubmed/30982859