faculty

Publications

High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: a prospective cohort study

Groups and Associations Kavsak PA, Walsh M, Sigamani A, Xavier D, Devereaux PJ, et al;
Clin Biochem 2011

OBJECTIVES:
To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay.
 
DESIGN AND METHODS:
We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults.
 
RESULTS:
Postoperatively 45% (95% CI: 39-50%) of patients had hs-TnT≥14ng/L and 22% (95% CI:17-26%) had an elevation (≥14ng/L) and change (>85%) in hs-TnT.
 
CONCLUSION:
Further research is needed to inform the optimal hs-TnT threshold and change in this setting.