Ms Chandrakala M
PhD Student
- Overview
- Projects
- Publications
- Other Contributions
PhD Scholar affiliated to Manipal Academy of Higher Education (MAHE), working on a research project titled “Deciphering the Role of Estrogen Receptor Beta in Breast Cancer Subtypes.” The project focuses on understanding the subtype-specific functions of estrogen receptor beta and its implications in breast cancer biology.
Qualification/ Education
- M.Sc
Bangalore University - B.Sc
Bangalore University
Experience
- Project Assistant
St John's Research Institute
17/11/2020 to 31/12/2022
India
Projects:
- MicroRNA 18a mediated epigenetic regulation of Estrogen receptor positive and negative breast cancer subtypes.
- To evaluate the role of circulating nuclei acids (DNA and miRNA) in breast cancer patients and associated prognosis.
- To evaluate the effects of skincare and haircare products on dermal and hair follicle cell lines (Cytotoxicity assays, Anti-oxidant assays, Melanin inhibition assays, Anti-tyrosinase activity).
- Profiling and characterization of molecular mechanism of chemosensitization of a synthetic chemical in Lung and Glioblastoma cell lines.
- Junior Research Fellow
St John's Research Institute
01/02/2023 to 31/01/2025
India
Field of Expertise
Molecular Biology Techniques
Nucleic acid and protein isolation and quantification, qPCR, Western blotting, immunofluorescence, and immunohistochemistry
Mammalian Cell Culture
Basic mammalian cell culture t
Fellowship & Membership
CSIR-UGC fellowship (2023 to 2028)
- Project Assistant
St John's Research Institute
17/11/2020 to 31/12/2022
India
Projects:
- MicroRNA 18a mediated epigenetic regulation of Estrogen receptor positive and negative breast cancer subtypes.
- To evaluate the role of circulating nuclei acids (DNA and miRNA) in breast cancer patients and associated prognosis.
- To evaluate the effects of skincare and haircare products on dermal and hair follicle cell lines (Cytotoxicity assays, Anti-oxidant assays, Melanin inhibition assays, Anti-tyrosinase activity).
- Profiling and characterization of molecular mechanism of chemosensitization of a synthetic chemical in Lung and Glioblastoma cell lines.
- Junior Research Fellow
St John's Research Institute
01/02/2023 to 31/01/2025
India
No areas of interest specified.
No groups and associations specified.
No project details available.
Elucidating the Role of MicroRNA-18a in Propelling a Hybrid Epithelial-Mesenchymal Phenotype and Driving Malignant Progression in ER-Negative Breast Cancer
Increased prevalence of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancer
An androgen receptor regulated gene score is associated with epithelial to mesenchymal transition features in triple negative breast cancers
Estimation of ALU Repetitive Elements in Plasma as a Cost-Effective Liquid Biopsy Tool for Disease Prognosis in Breast Cancer
The dynamic tumor-stromal crosstalk: implications of 'stromal-hot' tumors in the process of epithelial-mesenchymal transition in breast cancer
miR-18a Mediates Immune Evasion in ER-Positive Breast Cancer through Wnt Signaling
No Others Contributions details available.