Faculty & Staff

doctor

Ms Chandrakala M

PhD Student

  • Overview
  • Projects
  • Publications
  • Other Contributions

PhD Scholar affiliated to Manipal Academy of Higher Education (MAHE), working on a research project titled “Deciphering the Role of Estrogen Receptor Beta in Breast Cancer Subtypes.” The project focuses on understanding the subtype-specific functions of estrogen receptor beta and its implications in breast cancer biology.

Qualification/ Education

  • M.Sc
    Bangalore University
  • B.Sc
    Bangalore University

Experience

  • Project Assistant
    St John's Research Institute
    17/11/2020 to 31/12/2022
    India

Projects:

  • MicroRNA 18a mediated epigenetic regulation of Estrogen receptor positive and negative breast cancer subtypes.
  • To evaluate the role of circulating nuclei acids (DNA and miRNA) in breast cancer patients and associated prognosis.
  • To evaluate the effects of skincare and haircare products on dermal and hair follicle cell lines (Cytotoxicity assays, Anti-oxidant assays, Melanin inhibition assays, Anti-tyrosinase activity).
  • Profiling and characterization of molecular mechanism of chemosensitization of a synthetic chemical in Lung and Glioblastoma cell lines. 
  • Junior Research Fellow
    St John's Research Institute
    01/02/2023 to 31/01/2025
    India

Field of Expertise

Molecular Biology Techniques
Nucleic acid and protein isolation and quantification, qPCR, Western blotting, immunofluorescence, and immunohistochemistry

Mammalian Cell Culture
Basic mammalian cell culture t

Fellowship & Membership

CSIR-UGC fellowship (2023 to 2028)

  • Project Assistant
    St John's Research Institute
    17/11/2020 to 31/12/2022
    India

Projects:

  • MicroRNA 18a mediated epigenetic regulation of Estrogen receptor positive and negative breast cancer subtypes.
  • To evaluate the role of circulating nuclei acids (DNA and miRNA) in breast cancer patients and associated prognosis.
  • To evaluate the effects of skincare and haircare products on dermal and hair follicle cell lines (Cytotoxicity assays, Anti-oxidant assays, Melanin inhibition assays, Anti-tyrosinase activity).
  • Profiling and characterization of molecular mechanism of chemosensitization of a synthetic chemical in Lung and Glioblastoma cell lines. 
  • Junior Research Fellow
    St John's Research Institute
    01/02/2023 to 31/01/2025
    India

No areas of interest specified.

No groups and associations specified.

No project details available.

Elucidating the Role of MicroRNA-18a in Propelling a Hybrid Epithelial-Mesenchymal Phenotype and Driving Malignant Progression in ER-Negative Breast Cancer

Groups and Associations Nair MG, Mavatkar AD, Naidu CM, V P S, C E A, Rajarajan S, Sahoo S, Mohan G, Jaikumar VS, Ramesh RS, B S S, Jolly MK, Maliekal TT, Prabhu JS
Cells 2024
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Increased prevalence of hybrid epithelial/mesenchymal state and enhanced phenotypic heterogeneity in basal breast cancer

Groups and Associations Sahoo S, Ramu S, Nair MG, Pillai M, San Juan BP, Milioli HZ, Mandal S, Naidu CM, Mavatkar AD, Subramaniam H, Neogi AG, Chaffer CL, Prabhu JS, Somarelli JA, Jolly MK.
iScience 2024
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An androgen receptor regulated gene score is associated with epithelial to mesenchymal transition features in triple negative breast cancers

Groups and Associations Rajarajan S, Snijesh VP, Anupama CE, Nair MG, Mavatkar AD, Naidu CM, Patil S, Nimbalkar VP, Alexander A, Pillai M, Jolly MK, Sabarinathan R, Ramesh RS, Bs S, Prabhu JS
Transl Oncol 2023
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Estimation of ALU Repetitive Elements in Plasma as a Cost-Effective Liquid Biopsy Tool for Disease Prognosis in Breast Cancer

Groups and Associations Nair MG, Ramesh RS, Naidu CM, Mavatkar AD, V P S, Ramamurthy V, Somashekaraiah VM, C E A, Raghunathan K, Panigrahi A, Das M, Dhar SK, Prabhu JS
Cancers 2023
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The dynamic tumor-stromal crosstalk: implications of 'stromal-hot' tumors in the process of epithelial-mesenchymal transition in breast cancer

Groups and Associations Mavatkar AD, Naidu CM, Prabhu JS, Nair MG
Molecular Biology Reports 2023
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miR-18a Mediates Immune Evasion in ER-Positive Breast Cancer through Wnt Signaling

Groups and Associations Nair MG, D A, M C, Vp S, Patil S, Ce A, Mukherjee G, Kumar RV, Prabhu JS, Ts S
Cells 2022
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No Others Contributions details available.