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Infectious Diseases
- Introduction to Division
- Key Personnel
- Projects
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Infectious Diseases
The Infectious Disease Unit houses Research in immunological and epidemiological aspects of bacterial, viral and mycobacterial infections. The projects network with clinical departments of St. John’s Medical College and Hospital and few extra-mural institutions. The laboratory in the unit handles molecular biology in the realm of research and diagnostic services for the hospital. A level 3 containment facility enables work in Tuberculosis and other infectious diseases requiring such a facility. A bio repository unit facilitates storage of various kinds of clinical samples such as peripheral blood cells, plasma, DNA extracts, bacterial cultures, etc. at temperatures of -20deg C, -80deg C and in liquid nitrogen (ether-phase).
The Division of Infectious Diseases focuses on the biological, immunological and epidemiological aspects of viral, bacterial and parasitic diseases of public health importance. The lab is currently working on Dengue, HIV, Tuberculosis and Malaria both from the hospital and community setting.
Key Personnel
Unit Head
Professor & Head
Professor & Head / MicrobiologyDr. Mary Dias currently holds the position of Professor in the Department of Microbiol...
Core Staff
| S.I. No | Project Title | Project Lead | Year of Initiation |
|---|---|---|---|
| 1 | C-CAMP InDx CoE – Validation centre | Dr. Mary Dias, Dr. Mamatha. V | 2023 |
| 2 | Biomarker signatures for diagnosis for tuberculosis | Dr. Mary Dias | 2018 |
| S.I. No | Title | Authors | Journal Name | Publication Year |
|---|---|---|---|---|
| 1 | Risk factors for recognized and unrecognized SARS-CoV-2 infection: a seroepidemiologic analysis of the Prospective Urban Rural Epidemiology (PURE) study | Leong DP, Loeb M, Mony PK, Rangarajan S, Mushtaha M, Miller MS, Dias M, Yegorov S, V M, Telci Caklili O, Temizhan A, Szuba A, Abat MEM, Mat-Nasir N, Diaz ML, Khansaheb H, Lopez-Jaramillo P, Duong M, Teo KK, Poirier P, Oliveira G, Avezum Á, Yusuf S | Risk factors for recognized and unrecognized SARS-CoV-2 infection | 2024 |
| 2 | BCG revaccination in adults enhances pro-inflammatory markers of trained immunity along with anti-inflammatory pathways | Ahmed A, Tripathi H, van Meijgaarden KE, Kumar NC, Adiga V, Rakshit S, Parthiban C, Eveline J S, D'Souza G, Dias M, Ottenhoff THM, Netea MG, Joosten SA, Vyakarnam A | Iscience, 2023 | 2023 |
| 3 | Polyfunctional CD4 T-cells correlating with neutralising antibody is a hallmark of COVISHIELDTM and COVAXIN® induced immunity in COVID-19 exposed Indians | Rakshit S, Babji S, Parthiban C, Madhavan R, Adiga V, J SE, Chetan Kumar N, Ahmed A, Shivalingaiah S, Shashikumar N, V M, Johnson AR, Ramesh N, B RG, Asokan M, Mayor S, Kang G, D'souza G, Dias M, Vyakarnam A | NPJ Vaccines. 2023 | 2023 |
| 4 | Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD™ vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian adults | Rakshit S, Adiga V, Ahmed A, Parthiban C, Chetan Kumar N, Dwarkanath P, Shivalingaiah S, Rao S, D'Souza G, Dias M, Maguire TJA, Doores KJ, Zoodsma M, Geckin B, Dasgupta P, Babji S, van Meijgaarden KE, Joosten SA, Ottenhoff THM, Li Y, Netea MG, Stuart KD, De Rosa SC, McElrath MJ, Vyakarnam A | Frontiers in immunology, 2022 | 2022 |
| 5 | Immune profile and responses of a novel dengue DNA vaccine encoding an EDIII-NS1 consensus design based on Indo-African sequences | Sankaradoss A, Jagtap S, Nazir J, Moula SE, Modak A, Fialho J, Iyer M, Shastri JS, Dias M, Gadepalli R, Aggarwal A, Vedpathak M, Agrawal S, Pandit A, Nisheetha A, Kumar A, Bordoloi M, Shafi M, Shelar B, Balachandra SS, Damodar T, Masika MM, Mwaura P, Anzala O, Muthumani K, Sowdhamini R, Medigeshi GR, Roy R, Pattabiraman C, Krishna S, Sreekumar E. | Molecular Therapy, 2022 | 2022 |
| 6 | The Evolution of Regulatory Elements in the Emerging Promoter-Variant Strains of HIV-1 Subtype C | Bhange D, Prasad N, Singh S, Prajapati HK, Maurya SP, Gopalan BP, Nadig S, Chaturbhuj D, Jayaseelan B, Dinesha TR, Ahamed SF, Singh N, Brahmaiah A, Mehta K, Gohil Y, Balakrishnan P, Das BK, Dias M, Gangakhedkar R, Mehendale S, Paranjape RS, Saravanan S, Shet A, Solomon SS, Thakar M, Ranga U | Frontiers in microbiology, 2021 | 2021 |
| 7 | Innate Immune Cytokine Profiling and Biomarker Identification for Outcome in Dengue Patients | Pradeep SP, Hoovina Venkatesh P, Manchala NR, Vayal Veedu A, Basavaraju RK, Selvasundari L, Ramakrishna M, Chandrakiran Y, Krishnamurthy V, Holigi S, Thomas T, Ross CR, Dias M, Satchidanandam V | Frontiers in Immunology, 2021 | 2021 |
| 8 | Molecular detection of virulence markers to identify diarrhoeagenic Escherichia coli isolated from Mula-Mutha river, Pune District, India | Namachivayam SR, Dhawde RR, Macaden RS, Dias M, Birdi TJ. | Journal of Environmental Science and Health, Part A, 2021 | 2021 |
| 9 | A century of BCG: Impact on tuberculosis control and beyond | Ahmed A, Rakshit S, Adiga V, Dias M, Dwarkanath P, D'Souza G, Vyakarnam A | Immunological reviews, 2021 | 2021 |
| 10 | Using data from 'visible' populations to estimate the size and importance of 'hidden' populations in an epidemic: A modelling technique | Foss AM, Prudden HJ, Mitchell KM, Pickles M, Washington R, Phillips AE, Alary M, Boily MC, Moses S, Watts CH, Vickerman PT | National Library of Medicine | 2020 |
| 11 | Is a differentiated care model needed for patients with TB? A cohort analysis of risk factors contributing to unfavourable outcomes among TB patients in two states in South India | Washington R, Potty RS, Rajesham A, Seenappa T, Singarajipura A, Swamickan R, Shah A, Prakash KH, Kar A, Kumaraswamy K, Prarthana BS, Maryala BK, Sushma J, Dasari R, Shetty B, Panibatla V, Mohan HL, Becker M | National Library of Medicine | 2020 |
| 12 | Plasma metabolomic study in perinatally HIV-infected children using 1H NMR spectroscopy reveals perturbed metabolites that sustain during therapy | Kaur S U, Oyeyemi BF, Shet A, Gopalan BP, D H, Bhavesh NS, Tandon R | National Library of Medicine | 2020 |
| 13 | High frequency of exon 20 S768I EGFR mutation detected in malignant pleural effusions: A poor prognosticator of NSCLC | George D'Souza, Chirag Dhar, Vishal Kyalanoor, Lokendra Yadav, Mugdha Sharma , Mohammad Nawaz S, Sweta Srivastava | Cancer Rep (Hoboken) . | 2020 |
| 14 | Pathogen genomic surveillance of typhoidal Salmonella infection in adults and children reveals no association between clinical outcomes and infecting genotypes | Britto CD, Mathias S, Bosco A, Dyson ZA, Dougan G, Raveendran S, Abin VL, Jose S, Nagaraj S, Holt KE, Pollard AJ | National Library of Medicine | 2020 |
| 15 | Moraxella catarrhalis: A Cause of Concern with Emerging Resistance and Presence of BRO Beta-Lactamase Gene-Report from a Tertiary Care Hospital in South Indi | Raveendran S, Kumar G, Sivanandan RN, Dias M | National Library of Medicine | 2020 |
| 16 | Viral evolution in the cell-associated HIV-1 DNA during early ART can lead to drug resistance and virological failure in children | Gopalan BP, D'Souza RR, Rajnala N, Arumugam K, Dias M, Ranga U, Shet A | National Library of Medicine | 2019 |
| 17 | Tuberculosis notification in a private tertiary care teaching hospital in South India: a mixed-methods study | Siddaiah A, Ahmed MN, Kumar AMV, D'Souza G, Wilkinson E, Maung TM, Rodrigues R | National Library of Medicine | 2019 |
| 18 | Evidence for highly variable, region-specific patterns of T-cell epitope mutations accumulating in Mycobacterium tuberculosis strains | Ramaiah A, Nayak S, Rakshit S, Manson AL, Abeel T, Shanmugam S, Sahoo PN, John AJUK, Sundaramurthi JC, Narayanan S, D'Souza G, von Hoegen P, Ottenhoff THM, Swaminathan S, Earl AM, Vyakarnam A | National Library of Medicine | 2019 |
| 19 | Analysis of dengue specific memory B cells, neutralizing antibodies and binding antibodies in healthy adults from India | Gunisetty S, Nayak K, Chandra Rai R, Chawla Y, Reddy ES, Aggarwal C, Maheshwari D, Panda H, Ansari NA, Singh P, Kaur M, Dixit K, Sharma P, Bhatnagar P, Priyamvada L, Bhaumik SK, Ahamed SF, Vivek R, Ray P, Shet A, Coshic P, Lodha R, Kabra SK, Afroze D, Yousuf A, Ahmed R, Murali-Krishna K, Chandele A | National Library of Medicine | 2019 |
| 20 | Analysis of dengue specific memory B cells, neutralizing antibodies and binding antibodies in healthy adults from India | Gunisetty S, Nayak K, Chandra Rai R, Chawla Y, Reddy ES, Aggarwal C, Maheshwari D, Panda H, Ansari NA, Singh P, Kaur M, Dixit K, Sharma P, Bhatnagar P, Priyamvada L, Bhaumik SK, Ahamed SF, Vivek R, Ray P, Shet A, Coshic P, Lodha R, Kabra SK, Afroze D, Yousuf A, Ahmed R, Murali-Krishna K, Chandele A | National Library of Medicine | 2019 |
| 21 | Increased monocyte activation with age among HIV-infected long term non-progressor children: implications for early treatment initiation | D'Souza RR, Gopalan BP, Rajnala N, Phetsouphanh C, Shet A | National Library of Medicine | 2019 |
| 22 | Emergence of new genotypes and lineages of dengue viruses during the 2012-15 epidemics in southern India | Ahamed SF, Rosario V, Britto C, Dias M, Nayak K, Chandele A, Kaja MK, Shet A | National Library of Medicine | 2019 |
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